The Sayyids ruled from 1339 to 1561 for nearly 222 years. The Tughluq dynasty came to an end in1414 when Khizar Khan founded the Saiyyid dynasty in Delhi. Khizar assisted Timur during his invasion on India. Timur made Khizar Khan the governor of Lahore, Multan and Dipalpur as a reward. After the death of last Tughluq Mahmud Shah in 1412, Daullat Khan Lodhi accompanied Khizar Khan in order to occupy the throne of Delhi. In 1414 Khizar won the battle and established the rule. He ruled in the name of Timur and his successor Shah Rukh. During this time a number of states and provinces of the Delhi Sultanate declared their independence. So the first task was to control the situation and to control those revolts. He tried to reintegrate those provinces but failed. He conquered Gwalior, Gujrat and Jaunpur. In 1421 he attacked Mewat. During the tenure ship of Khizar the Delhi Sultanate was reduced to Sindh, Western Punjab and Western Uttar Pradesh.

His son Mubarak Shah succeeded him in 1421. His reign was full of internal and external revolts. His successors, nephew Muhammad shah and Muhammad's son Alauddin Alam Shah were marked by political instability. The territories of the empire were reduced to a distance of ten mile from Delhi to Palam.

The era of Saiyyid dynasty came to an end in 1451 as Buhlul Lodhi occupied Delhi. This reign was full of revolts and confusions.