Kazi Syed Karimuddin was born on 19th July 1899, in Yavatmal District of Maharashtra.His parents were Kazi Syed Nasiruddin and Qadir-un-nissa Begum. Kazi Syed Karimuddin was eduacted at Aligarh Muslim University and obtained a degree in law.He started practising law and became a well known criminal lawyer.

Kazi Syed Karimuddin was the member of the Indian National Congress.He was also selected as the member of the Constituent Assembly of India. Kazi Syed Karimuddin was elected as the member of Madhya Pradesh Legislative Assembly.He was the member of Rajya Sabha from 1954 to 1958. Kazi Syed Karimuddin pased away on 14th November 1977.