According to the Indian Census report of 2001, Mangalvedhe had a population of 21, 694. Males comprises of 52% of the population and females account for the remaining 48%. In Mangalvedhe, 13% of the population is less than six years of age. The average literacy rate of Mangalvedhe is 68%, which is higher than the national average literacy rate, which is 59.5%. The male literacy rate is 76% and the female literacy rate is 60%.
A prominent religious destination, Mangalvedhe is the birthplace of Shri Jayatirtha also called Teekacharya, a famous saint of the Dvaita school of Vedanata. Vithal-Rukmini Temple at Pandharpur, Trimbakeshwar Temple and Vishnupad Temple are other attractions for devotees in the vicinity.