He started his career, as a teacher of medicine. He was the professor of Tufts University and Boston University Schools of Medicine. Deepak Chopra was also appointed as the chief of New England Memorial Hospital in Stoneham, Massachusetts, and Boston Regional Medical Center in Boston, Massachusetts.Apart from teaching he also practised privately.
He returned to India and deeply influenced by Ayurvedic doctor Vaidya Brihaspati Dev Triguna and became pioneer of Transcendental Meditation movement. After that he started mind-body treatment and became the director of Sharp Institute for Human Potential and Mind-Body Medicine in San Diego.
In 1996 Deepak Chopra established The Chopra Center in La Jolla with the help of his friend Dr. David Simon.In 2002 the head quarter of the centre was transffered to La Costa.In this year he also opened a new branch in New York.
From 1987 he started writing books on his favourite subject Body -Mind treatment.Through his books he strongly advocated that there is a crucial intermingling between mind and body, and said meditation and self-awareness is the primary remedies of illness. In one hand he was deeply moved by the spiritualism Vedanta and the Bhagavad Gita and on the other hand he was inspired by quantum physics.He wrote many spiritual books also.Deepak Chopra brought together the best of ancient wisdom and modern science His mission is to" bridge the technological miracles of the west with the wisdom of the east".
He has also written novels and edited collections of spiritual poetry from India and Persia.Besides he wrote more than 100 audio, video and CD-Rom titles. His books have been translated into several languages all over the world. His famous books are -Creating Health (1987),Quantum Healing: Exploring the Frontiers of Mind/Body Medicine (1989), Unconditional Life: Mastering the Forces That Shape Personal Reality(1991) ,Perfect Health: The Complete Mind/Body Guide (1991),Ageless Body, Timeless Mind : The Quantum Alternative to Growing Old (1993) ,Creating Affluence: Wealth Consciousness in the Field of All Possibilities (1993),The Seven Spiritual Laws of Success: A Practical Guide to the Fulfilment of Your Dreams (1994).,The Way of the Wizard: Twenty Spiritual Lessons in Creating the Life You Want (1995),The Path to Love: Renewing the Power of Spirit in Your Life (1997),Everyday Immortality: A Concise Course in Spiritual Transformation (1999),The Angel is Near: A Novel (2000),The Deeper Wound(2001 ), Grow Younger, Live Longer(2001), Golf for Enlightenment,(2003,) Synchrodestiny(2003), The Book of Secrets(2004), Peace Is the Way (2005), Power Freedom and Grace(2006), Life After Death(2006), Buddha(2007). His well known music and videoCDs are- A Gift of Love, Soul of Healing Meditations, A Gift of Love II, Chakra Balancing, Seven Spiritual Laws of Success, The Way of the Wizard, God and Buddha, Soul of Healing.In 2007 he wrote a comic novel named India Authent(virgin comics).
Time Magazine described Chopra as one of the 100 heroes and icons of the century, and credited him as "the poet-prophet of alternative medicine." Entertainment Weekly described Deepak Chopra as "Hollywood's man of the moment, one of publishing's best-selling and most prolific self-help authors." Deepak Chopra has been a keynote speaker at several academic institutions including Harvard Medical School, Harvard Business School, Harvard Divinity School, Kellogg School of Management, Stanford Business School and Wharton.