Karan also made his Bollywood debut as the brother of Abhishek Bachchan in the superhero movie, Drona and the actor wants to brush up with nuances of acting before moving ahead in his career. He also feels that theatre is the best medium for an actor as the response of it lies in the instant judgment. Karan Mehra sometime back also signed the Sahara One show, Sati. In this serial, he plays the character of a fun-filled, easy-going talk show host who is engaged in the task of inviting celebrities and high profile elite personas to his show and also gets them to talk about different aspects and phases of their individual and related lives. Karan Mehra also plays a very good friend of the female protagonist of the show Sati and also harbours a soft corner for her due to her pleasant demeanour and strong determination. Their professional relationship is also very well portrayed. Though the show did not do too well he has received many applauds for his brilliant performances. Many have already acknowledged his classy performances; Bollywood superstars and Abhishek Bachchan recently congratulated him while he was shooting at Kalamisthan for Betiyaan.
Karan Mehra, an extremely striking actor, has already carved a special niche for himself in the hearts of the audiences and in the near future also he is expected to scale new heights of success.