The Gauhati Medical College (GMC) was established in 1960, as the second medical college in the state of Assam. The college is situated in Guwahati and it was established as the demands for health care and health education and the need for more medical colleges in Assam was keenly felt. The college was established in the vacant Ayurvedic College buildings and the Physical Education Training buildings at Jalukbari, Guwahati. The State Government of Assam gave the responsibilities to make all necessary arrangements for starting the preclinical classes at the Gauhati Medical College (GMC), to the Assam Medical College & Hospital, Dibrugarh. The functioning of the Gauhati Medical College was formally inaugurated from 20th September, 1960. The college started its operations in its present campus in Narakachal Hill from September, 1968. The Gauhati Medical College Hospital started its operations at its permanent site at the Narakachal foot hill in 1984.

The Gauhati Medical College (GMC), Guwahati is affiliated to the Guwahati University and it is also recognised by the Medical Council of India (MCI). The college has several departments including the departments of Pathology, Pharmacology, Medicine, Surgery, Obstetrics & Gynecology, Ophthalmology, E.N.T, Radiology, Social & Preventive Medicine and Forensic Medicine. The college offers courses in Medical, Medical Research and Pharmacy. The courses are offered in both the undergraduate and postgraduate levels and the college offers some Diploma and other courses, as well. The college started offering postgraduate courses from 1969. The postgraduate courses offered by the college are M.S. in Anatomy, Surgery, ENT, Obstetrics & Gynecology, Ophthalmology and Orthopedics. Apart from that, M.D. courses in Anesthesiology, Biochemistry, Community Medicine, Dermatology, Forensic Medicine, Medicine, Microbiology, Pathology, Pediatrics, Pharmacology, Physiology, Psychiatry, and Radio Diagnosis, are also offered in the Gauhati Medical College (GMC), Guwahati.

The Bachelors Degree of this college got recognition from the General Medical Council of U.K. in 1969. The required qualification for getting admitted in the college is H.Sc/12th/Pre-Uni/Pre-Degree, 2 yrs exam or an equivalent examination with English, Physics, Chemistry and Biology with 50% marks in aggregate of science subjects in the first attempt. The students are admitted in the GMC, Guwahati, strictly on the basis of merit in the state level admission test. The Gauhati Medical College has been enjoying a prestigious status in the country for its academic pursuits and patients care, and also as a referral centre for speciality and super speciality treatment.