The Tapti River basin covers an area of 65,145 km² that makes up almost two percent of the total area of India. The basin lies in the states of Maharashtra, coveri8ng an area about 51,504 km², Madhya Pradesh with 9,804 km² surface area and Gujarat covering 3,837 km² of land. The basin lies mostly in the northern and eastern districts Maharashtra state, including Amravati, Akola, Buldhana, Washim, Jalgaon, Dhule, Nandurbar, and Nashik districts, but also includes the Betul and Burhanpur districts of Madhya Pradesh and the Surat district of Gujarat.

The rivers of Tapti river basin include Shiva River, Gomai River, Vaki River, Arunavati River, Burai River, Panzara River, Bori River, Aner River, Girna River, Khandu River , Waghur River, Purna River, Nipani River, Mann River, Nesu River, Aas River, Umaa River and Shahanur River.