Vani Jayaram has been considered as one of the highly accomplished female playback singers in India. She has sang in many languages like, Tamil, Telugu, Malayalam, Marathi, Hindi and Kannada. Acknowledging her talent she has been conferred the National Film Awards for three times. Vani Jayaram possesses `an impeccable style of singing and pronunciation, the ability to sing in a multitude of languages with ease`. Vani Jayaram has received rigorous Carnatic music training under the great tutelage of Kadalur Srinivasa Iyengar, T.R. Balasubramanian and R.S. Mani.

Vani Jayaram has received formal classical training in singing under Ustad Abdul Rahman Khan. She is a qualitative singer whose versatility ranges withing a large scope of music. Her rendarings ranges from classical songs in Carnatic and Hindustani styles, ghazals, light and pop songs and some very popular folk songs as well. This child prodigy first executed for All India Radio, Madras, at the age of eight. Since her childhood, she always possessed an yearning for the career in film playback singing. After her marriage to Jairam when they moved to Mumbai, it seemed as if her dream came true.

It was the year 1970, when the veteran hindi film music director, Vasant Desai selected her to sing for the hindi feature film Guddi. Three songs has been recorded on her voice. Her song from the film, `Bol Re Papi Hara,` was completely based on the hindustani raga Miyan Malhar. This song made her identity a household name in the different corners of India. After executing this song she has been conferred many accolades like, Tansen Samman (for best classical-based song in a hindi film,) The Lions International Best Promising Singer, The All India Cinegoers Association, and the All India Film-goers Association awards for the Best Playback Singer in the year 1971.

Under the music direction of S.M.Subbaiah Naidu in the year 1973, Vani Jayaram has recorded her first Tamil song for the Tamil film Thaiyum Seiyum. Besides Hindi and Tamil, she has sung songs in Gujarati, Marathi, Marwari, Hariyanvi, Malayalam, Kannada, Telugu, Oriya, Bengali and Tulu languages as well. For this kind of outstanding quality, she has been conferred many highly esteemed awards like, Best Female Playback Singer for states of Gujarat (in the year 1975), Tamil Nadu (in the year 1980) and Orissa (in the year 1984). In the year 1975, Vani Jayaram was nominated for the Indian President`s National Award for Best Female Playback Singer for the year. This award was given to her for for her work in M.S. Viswanathan`s Aboorva Ragangal (Tamil).

Vani Jayaram has also sang in the Pt. Ravi Shankar scored film Meera, which brought her the Film World (1979) Cine Herald (1979) and Filmfare (1980) awards for Best Playback Singer in Hindi. Vani Jayaram has won her second National Award as Best Playback Singer of the year 1980 for the film Shankarabharanam (Telugu). The music of that film was scored by K.V. Mahadevan. She won her third National Award for Best Playback Singer of the year 1991 again for K.V. Mahadevan`s Swati Kiranam. She has also bagged the honor to be the youngest artiste to be awarded the Sangeet Peet Samman.

Vani Jayaram has sung for the movies like, Swathi Kiranam (released in the year 1992); Pelli Pustakam (released in the year 1991); Gulabi Raaten (released in the year 1990); Bava Marudula Sawal (released in the year 1988); Agni Nakshatram (released in the year 1988); Loose Loose Arappiri Loose (released in the year 1988); Swarnakamalam (released in the year 1988); Damit Katha Adam Thirigindi (released in the year 1987); Aradhana (released in the year 1987); Naradhan Keralathil (released in the year 1987); Sruthi Layalu (released in the year 1987); Waqt Ka Shahenshah (released in the year 1987); Sri Shirdi Saibaba Mahathyam (released in the year 1986); Nirakkoottu (released in the year 1985); Wafadaar (released in the year 1985); Eeran Sandhya (released in the year 1985); Muhurtham Pathnonnu Muppathinu (released in the year 1985); Koodum Thedi (released in the year 1985); Mugila Malligey (released in the year 1985); Mutharamkunnu P.O. (released in the year 1985); Vasantha Sena (released in the year 1985); Aakhri Sangram (released in the year 1984); Appunni (released in the year 1984); Athirathram (released in the year 1984); Koottinilamkili (released in the year 1984); Naalai Unathu Naal (released in the year 1984); Sandhya Mayangum Neram (released in the year 1984); Swanthamevide Bandhamevide (released in the year 1984); Attakkalasam (released in the year 1983); Bhookambam (released in the year 1983); Kattathe Kilikoodu (released in the year 1983); Kuyiline Thedi (released in the year 1983); Marakkillorikkalum (released in the year 1983); Prathigna (released in the year 1983); Aakrosam (released in the year 1982); Kurukkante Kalyanam (released in the year 1982); Padayottam (released in the year 1982); Ponmudy (released in the year 1982); Ponnum Poovum (released in the year 1982); Pooviriyum Pulari (released in the year 1982); Ariyappedatha Rahasyam (released in the year 1981); Palangal (released in the year 1981); Parvathi (released in the year 1981); Seethakoka Chilaka (released in the year 1981); Circus Ramudu (released in the year 1980); Manjil Virinja Pookkal (released in the year 1980); Subhodayam (released in the year 1980); Idi Kathakaadu (released in the year 1979); Meera (released in the year 1979); Aavesham (released in the year 1979); Guppedu Manasu (released in the year 1979); Jeevitam Oru Gaanam (released in the year 1979); Mamangam (released in the year 1979); Sarapanjaram (released in the year 1979); Shankarabharanam (released in the year 1979); Maro Charithra (released in the year 1978); Aaina (released in the year 1977); Anthuleni Katha (released in the year 1976); Seeta Kalyanam (released in the year 1976); Apoorva Raagangal (released in the year 1975); Picnic (released in the year 1975); Raagam (released in the year 1975); Jurm Aur Sazaa (released in the year 1974); Parinay (released in the year 1974); Chhalia (released in the year 1973); Ek Mutthi Aasmaan (released in the year 1973); Swapnam (released in the year 1973) ; Pakeezah (released in the year 1972); Bansi Birju (released in the year 1972); Guddi (released in the year 1971).